Endocrine Abstracts

Introduction: Primary squamous cell carcinoma (PSCC) of thyroid is a rare type of thyroid malignancies because thyroid gland lacks squamous epithelium. It is seen in <1% of all thyroid malignancies. During last 30 years only about 90 cases were published. PSCC is an aggressive tumour as well as rare.Case report: We present a 60-year-old female who had been followed up for multiple nodules in thyroid in our outpatient clinic for 2 years. Her serum fre...

Classic thyroid hormone resistance (THR) occurs per every 400 000 live birth. THR should be considered along with TSH-producing adenomas when normal or high levels of TSH not consistent with hyperthyroidism is present. A 45-year-old female patient who was operated three times for multinodulary goitre had been treated with L-thyroxine. Mamillary biopsy had performed after detection of mass localized in right breast by mammography performed during regular follow-u...

Introduction: Primary thyroid lymphomas are rare cancers and account 1–5% of all thyroid cancers and 3% of all extranodal non hodgkin lymphomas (NHLs). We aimed to present cases of thyroid lymphoma encountered in our clinic.Case 1: A 54-year-old female patient admitted with pain and swallow on the cervical region. In ultrasonographic (USG) thyroid examination, it was found that both thyroid lobes were very large with routh parenchyme consis...

Background: Differentiated thyroid cancer is the most frequent thyroid tumor. Combinations of follicular carcinoma and papillary carcinoma are seen. Functional pituitary adenoma coexisting with differentiated thyroid carcinoma was reported previously in literature. We report a 47-year-old women with three different synchronous endocrine tumors; papillary thyroid cancer, follicular thyroid cancer, and prolactinoma.Case: A 47-years-old female patient was a...

Background: Incretin-based therapy is increasingly used in the management of type 2 diabetes mellitus. Although dipeptidyl peptidase-4 inhibitors (gliptins) are well tolerated, side effects can be observed in various body systems. Here we report three cases of drug-induced skin eruption with strong itching of the gliptins plus metformin combination therapy.Case reports: A 59-year-old woman and a 57-year-old man, who had been using vildagliptin plus metfo...

Multiple myeloma is a neoplastic disorder arising from plasma cells in the bone marrow. Plasma cell tumors, plasmacytomas, are uncommon in the brain and occur usually in the leptomeninges with or without parencymal involvement. Extramedullary plasmacytomas are very rarely located in the sella and can be misdiagnosed as a nonfunctioning pituitary adenoma. We report an illustrative case with multiple myeloma who was diagnosed having sellar plasmacytoma resembling a nonfunctionin...

Sex reversal syndrome (SRS) is a kind of human genetic disease about gender dysplasia, which is characterised by inconsistency between gonadal sexuality and chromosome sexuality. The clinical types include 46, XY female SRS and 46, XX male SRS. The early studies of human gonadal differentiation found that human Y chromosome contains testis-determining factor (TDF) found that the sex-determining region Y (SRY) gene, which is located in Y chromosome, was the best candidate gene ...

Diabetes mellitus (DM) is one of the most serious comorbidities in kidney transplant recipients. New onset diabetes after kidney transplantation (NODAT) is a common and an important complication following solid organ transplantation. It is associated with poor graft function and increased cardiovascular complications. Therefore, management of hyperglycemia after transplantation is important to reduce diabetes-related risks. We aimed to compare the effects of pre-existing DM an...

Introduction: The non-insulinoma pancreatogenous hypoglycemia syndrome (NIPHS) identifies a group of hyperinsulinemic hypoglycemic patients with unique clinical, diagnostic, surgical, and pathologic features. A selective arterial calcium stimulation test (SACST) with hepatic venous sampling can be performed to distinguish between a focal abnormality (insulinoma) and a diffuse process (islet-cell hypertrophy/nesidioblastosis). In patients with insulinoma, the response is positi...

Bone mineral disorders usually resolve after successful kidney transplantation. Serum calcium (Ca), phosphorus (P) and parathyroid hormone (PTH) levels tend to normalize within time. Serum Ca levels >10.2 mg/dL and PTH levels >150 pg/mL at 6th−12th months of transplantation is defined as persistent hypercalcemia and persistent hyperparathyroidism (PHPT) in recipients with normal graft function. Reported persistent hypercalcemia prevalence varies in wide range bet...